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Une nouvelle étude vient s’ajouter au nombre croissant de preuves de l’utilité des psychédéliques dans le traitement des troubles mentaux.
L’étude, réalisée à l’Université de Colombie-Britannique, porte sur le potentiel thérapeutique du microdosage de psilocybine, ou “champignons magiques”.
Selon un communiqué de presse de Quantified Citizen, les principales conclusions sont que le microdosage de psilocybine est une aubaine pour l’humeur et la santé mentale et pourrait avoir une importance particulière pour les personnes de plus de 55 ans.
Les résultats de l’étude ont été publiés dans nature.com
La recherche a montré que les personnes qui ont pris des microdoses de psilocybine pendant 30 jours ont montré de plus grandes améliorations de l’humeur, de la santé mentale et des capacités psychomotrices que celles qui n’ont pas pris de microdoses.
Une constatation spécifique aux personnes de plus de 55 ans a été faite : le microdosage était associé à une plus grande amélioration des performances psychomotrices, par rapport aux non-microdosers.
Ces améliorations étaient plus importantes lorsque la psilocybine était associée à la crinière de lion (un type de champignon censé stimuler les fonctions mentales) et à la niacine (vitamine B3), plutôt qu’à la psilocybine seule.
L’étude a suivi 953 personnes prenant régulièrement de petites quantités de psilocybine et un second groupe de 180 personnes qui ne prenaient pas de microdoses.
Neuroscience news rapporte qu’au cours de l’étude de 30 jours, les participants ont rempli plusieurs évaluations sur l’humeur, la santé mentale et la cognition.
Ceux qui prenaient des microdoses ont constaté des améliorations plus importantes dans tous ces domaines que ceux qui ne prenaient pas de microdoses.
Parmi les microdoseurs qui ont exprimé des préoccupations en matière de santé mentale, les scores de dépression, d’anxiété et de stress ont diminué après 30 jours ; les microdoseurs ont également montré une plus grande augmentation de l’humeur positive et une plus grande diminution de l’humeur négative au bout de 30 jours, par rapport à ceux qui ne prenaient pas de microdose.
L’étude a été menée par le Dr Zach Walsh et l’étudiant en doctorat Joseph Rootman de l’Université de Colombie-Britannique Okanagan. Il s’agit de la dernière étude du projet Microdose.me, une étude mondiale de microdosage mobile à laquelle participent 84 pays et 19 000 personnes.
Les personnes intéressées peuvent télécharger l’application Quantified Citizen pour y prendre part.
Comme l’a déclaré le Dr Walsh à Neuroscience News, “nos résultats concernant l’amélioration de l’humeur et la réduction des symptômes de dépression, d’anxiété et de stress s’ajoutent à la conversation croissante sur le potentiel thérapeutique du microdosage.”
On pense qu’il s’agit de la plus grande étude longitudinale de ce type à ce jour sur le microdosage de psilocybine, et l’une des rares études à engager un groupe de contrôle.
L’étude a noté qu’il y avait des améliorations associées dans la capacité psychomotrice parmi les microdoseurs de stacking, par rapport à ceux qui utilisent seulement la psilocybine.
Parmi les tests de cognition figurait le test de la capacité psychomotrice par tapotement du doigt effectué sur un smartphone, le même test utilisé pour prédire les troubles neurodégénératifs tels que la maladie de Parkinson.
Dans ce test, l’association de psilocybine, de crinière de lion (HE) et de B3 s’est avérée particulièrement efficace pour les participants âgés.
Les adultes de plus de 55 ans qui ont pris des microdoses de champignons à psilocybine – plus HE et B3 – ont montré les plus fortes augmentations (environ 40 %) du nombre total de tapotements après environ un mois, par rapport aux non-microdoseurs et à ceux qui ont pris des microdoses de psilocybine seule.
L’article indique clairement, cependant, que bien que ces résultats puissent être décrits comme suggestifs, “ils ajoutent néanmoins une crédibilité préliminaire aux rapports anecdotiques des bénéfices de la combinaison spécifique de psilocybine, HE et B3”.
Source: https://torontosun.com/news/national/new-study-shows-benefits-of-microdosing-psilocybin
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